A patient-centered, combination intervention to support adherence to HIV pre-exposure prophylaxis during pregnancy and breastfeeding: a randomized pilot study in Malawi

The intervention was integrated Next Step Counseling to identify relevant needs and help participants generate their own solutions for improving, facilitating, and sustaining well-being, sexual health, and drug adherence, as well as optional engagement of an adherence supporter. Study retention remained high at both three months and six months after initiation. There were no significant differences of adherence between the intervention group and control groups at three months or six months. Fewer than 1/3 of participants had confirmed adherence of >=4 doses/week.

Resource Details

Study Type
Pilot study, Randomized clinical trial (RCT)
Year
2024
Population
HIV-uninfected women, Pregnant Women
Author
Chi BH, Saidi F, Graybill LA, Phanga T, Mollan KR, Amico KR, Freeborn K, Rosenberg NE, Hill LM, Hamoonga T, Richardson B, Kalua T, Phiri S, Mutale W.

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